%0 Journal Article
%A Manga, Isaac Akhénaton Manga
%A Sall, Fatimata Bintou Sall
%A Diouf, Marie Pierre Diouf
%A Tairou, Fassiatou Tairou
%A Seck, Amadou Seck
%A Diop, Seynabou Diop
%A Mhadji, Abdoulkarim Mhadji
%A Ndiop, Médoune Ndiop
%A Gueye, Alioune Badara Gueye
%A Kaly, Stander Nabi Kaly
%A Diallo, Ibrahima Diallo
%A Sene, Doudou Sene
%A Sow, Doudou Sow
%A Faye, Babacar Faye
%A Ndiaye, Jean Louis Ndiaye
%D 2026
%J African Journal of Parasitology, Mycology and Entomology

%@ 1987-1473

%V 3
%N 2
%P 15

%T Ten Years of Seasonal Malaria Chemoprevention in Senegal: Scale-Up Process, Coverage, Tolerability—Ten Years of SMC in Senegal
%M doi:10.35995/ajpme03020015
%U https://ajpme.jams.pub/article/3/2/299
%X Background: Since 2013, Senegal has implemented seasonal malaria chemoprevention (SMC) with sulfadoxine–pyrimethamine plus amodiaquine (SPAQ) to reduce malaria among children under ten years of age. Over the past decade, SMC has become a cornerstone of malaria prevention, contributing to notable reductions in malaria incidence and mortality. Methods: This retrospective descriptive analysis of routine program data summarizes ten years of implementation, scaling up and adverse event monitoring of SMC in Senegal. Data were drawn from annual epidemiological bulletins and feedback reports from the National Malaria Control Programme (NMCP) between 2013 and 2021. These documents were analyzed to describe key stages of adoption, geographical expansion, and coverage trends. Tolerability and safety were assessed using adverse event (AE) reports documented by the national poison control center, which evaluates causality for suspected SPAQ-related events. Findings: Between 2013 and 2017, only the first daily dose of SPAQ was administered under directly observed treatment (DOT) by community health workers, while parents administered the remaining doses. Since 2019, all three doses have been administered under DOT. Coverage generally met or exceeded the national 95% target, although a temporary disruption occurred during health worker strikes in 2018. AE incidence remained very low (<0.5%), with most events being mild and only 19 serious cases reported over the ten-year period. Conclusion: Senegal’s decade-long SMC program achieved broad geographic expansion, sustained high coverage, and excellent tolerability. These results underscore the effectiveness of community-based delivery and the importance of sustained political and logistical support to consolidate malaria control gains.