%0 Journal Article %A Bédia-Tanoh, Akoua Valérie Bédia-Tanoh %A Konaté-Touré, Abibatou Konaté-Touré %A Vanga-Bosson, Abo Henriette Vanga-Bosson %A Miezan, Assohoun Jean Sebastien Miezan %A Koné, Estelle Gnanyo Massafoma Koné %A Kassi, Fulgence Kondo Kassi %A Kiki-Barro, Pulchérie M. Christiane Kiki-Barro %A Angora, Etienne Kpongbo Angora %A Djohan, Vincent Djohan %A Menan, Hervé EI Menan %A Yavo, William Yavo %D 2026 %J African Journal of Parasitology, Mycology and Entomology %@ 1987-1473 %V 4 %N 2 %P 3 %T Increase in Adherence and Efficacy of Intermittent Preventive Treatment (IPT) with Sulfadoxine–Pyrimethamine Among Pregnant Women in Bouna from 2021 to 2024 %M doi:10.35995/ajpme04020003 %U https://ajpme.jams.pub/article/4/2/300 %X Introduction: There are limited scientific data on the effectiveness of malaria control strategies among pregnant women in Bouna. This study was initiated to evaluate the efficacy of Intermittent Preventive Treatment with Sulfadoxine–Pyrimethamine (IPT-SP) among pregnant women in Bouna from 2021 to 2024. Methods: This study compiled data from two cross-sectional studies assessing the effectiveness of IPT-SP. These studies involved parturients received at the maternity ward of Bouna General Hospital in 2021 and 2024. Data were collected using a structured questionnaire, and plasmodial infestation was detected through optical microscopy. Results: The adherence rate for the third dose of SP (SP3) was 59.6% (143/240) in 2021 compared with 62.1% (149/240) in 2024. Plasmodial indices in 2021 were 13.8%, 11.7%, 8.3%, and 11.3% in venous blood, placental blood, cord blood, and placental smear, respectively, compared to 6.7%, 5.8%, 2.1%, and 6.3% in 2024. Data analysis revealed that attending fewer than four antenatal care (ANC) visits was associated with a low adherence rate to IPT-SP (2021: OR = 6.07; CI: [3.05–12.08]; p = 0.0001; 2024: OR = 43.66; CI: [20.29–93.98]; p = 0.0001). Factors such as maternal age (2021: p = 0.034; 2024: p = 0.030), parity (p = 0.001), gravidity (2021: p = 0.0001; 2024: p = 0.009), IPT-SP intake (2021: p = 0.032; 2024: p = 0.031), presence of anomalies (p = 0.003), and plasmodial infestation were associated with the occurrence of low birth weight. Conclusion: This study confirms the efficacy of IPT-SP. However, regular monitoring of its effectiveness and the exploration of new strategies for malaria control among pregnant women are recommended.